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Chinese equities fell for the second consecutive trading day on Friday led by a slump of health-care shares on profit taking.
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The Shenzhen Component Index went down 1.93 percent to end at 9,966.54.
Total turnover expanded to 145.93 billion yuan ($21.37 billion) from 126.96 billion yuan on the previous trading day.
Losers outnumbered gainers by 800 to 61 in Shanghai and 912 to 51 in Shenzhen.