Rafael Nadal has withdrawn from next week's Rotterdam Open after being advised by doctors to rest, the Spanish world No 6 said on Thursday.
Nadal, who lost in five sets to perennial rival Roger Federer in last month's Australian Open final, was left off Spain's Davis Cup squad for its World Group first-round tie against Croatia last weekend due to fatigue.
"I am very sorry to announce I won't be able to play in Rotterdam next week," Nadal said on Twitter.
"After last year's absence from some tournaments, I started this season well and made a significant effort during the Australian swing.
"It's because of this that my doctors have strongly advised me to take it easy and give enough rest to my body before competing again to avoid further injuries.
"I fully understand that the Dutch fans will be disappointed."
A wrist injury cut short Nadal's season in 2016.
Federer got the better of him in an epic Australian Open final, winning 6-4, 3-6, 6-1, 3-6 and 6-3.
Nadal should be ready to resume play at Acapulco in the week beginning Feb 27.