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The US Central Command (CENTCOM) said in a statement on Wednesday said the airstrikes destroyed an armored personnel carrier, armed vehicles and artillery piece belonging to the militant group.
The airstrikes were part of nine overall strikes in Syria over the last two days conducted with partner United Arab Emirates, using bomber, fighter, and remotely piloted aircraft, it said. "All aircraft exited the strike areas safely," it added.
The strikes near Kobani appear to have pushed back the militant group, which had appeared set to seize the Syrian town bordering Turkey after a three-week assault. Airstrikes in the area redoubled after the Islamic State hoisted its black flag on the eastern edge of Kobani on Monday.
Two other strikes targeting Islamic State near Raqqa, Islamic State's de facto capital in Syria, hit a training camp for the militants and the group's fighters there, according to CENTCOM. Another strike near Deir al-Zor destroyed a tank, it said.
The United States, Britain and the Netherlands also conducted five strikes against Islamic State in Iraq on Tuesday and Wednesday using fighter and remotely piloted aircraft, the statement said.