"Some of them are promising an all-out effort to stop him. So his path to party unification will need to overcome those individuals," he added.
On the Democratic side, Clinton is expected to sweep the southern US states on Super Tuesday, Zelizer said, but added that Clinton's only rival, Senator Bernie Sanders, will win or do very well in states such as Vermont, Massachusetts and perhaps Minnesota and Oklahoma.
"That said, I think the main issue with Sanders is how long this continues and how bitter the battle becomes," Zelizer said.
"I think he will continue through March regardless, given that there are some northern states where he might find support," he said.
West also said Clinton is in great shape for the Democratic Party nomination.
He said Clinton should do well on Super Tuesday because half of the states are in the South and African Americans constitute a major part of the Democratic electorate. "Since she is doing well with that group, Sanders' only hope is to sweep the states that are largely white," he said.
After Super Tuesday, Clinton is expected to pivot from Sanders to Trump and focus a lot of her upcoming speeches on why Trump would not make America great, West said, referring to the Trump campaign slogan "Make America Great Again!"