China National Chemical Corp's $43 billion bid for Swiss agrichemicals maker Syngenta makes up almost 40 percent of this year's $111.6 billion total, but even without that deal the pace has quickened.
Bankers and lawyers say there could, however, be some slowdown in the second half, as mainland buyers face heightened scrutiny at home and abroad.
China International Capital Corp, the country's biggest investment bank, expects outbound deals to hit $150 billion this year.
Chinese acquirers announced $111.5 billion worth of deals in 2015 from 632 transactions, according to Thomson Reuters data. Completed deals, on which banks are paid fees, last year stood at $73 billion, compared with $45.6 billion so far this year.
"We expect outbound M&A activities will continue to rise, but not at the nose-bleeding rate of the first quarter of 2016," said David Wu, head of corporate finance, China, for ING Bank.
Uncertainty surrounding the outcome of this week's referendum in Britain over its membership of the European Union and the upcoming US presidential elections in November are factors likely to slow Chinese overseas purchases, bankers say.
After many years of focusing on the booming domestic economy, Chinese companies are increasingly looking to diversify their revenues as growth at home slipped to a 25-year low.
Chinese state-owned and private companies are also looking to upgrade their manufacturing prowess with overseas technology.
Other big purchases announced by China Inc this year include HNA Group's $6.3 billion acquisition of Ingram Micro Inc and Haier Group's $5.4 billion bid for General Electric Co's appliances unit.
"Whether it be from the private sector, government or even middle market firms, this expansion is strategic and long-term focused," said John Kim, head of M&A, Asia ex-Japan at Goldman Sachs.
"The appetite is particularly voracious for technology, media, healthcare and financial services, and for the foreseeable future it won't be going away," he added.