"I know that a lot of people that say that they're Christians — you know, we don't always represent, and we don't always live it and we do sometimes some very stupid things, and you know we're not doing a good job," said Franklin, wearing blue jeans with a black velvet tuxedo jacket. "I want to make sure that when you see my life that it's a life that I'm gonna be proud of."
Talk-show host Jimmy Kimmel kicked off the three-hour ceremony at the Shrine Auditorium, televised live on ABC, with a skit that placed a ringer for Spears' ex, Kevin Federline, into a wooden crate dumped into the ocean. Kimmel cracked that Federline was the world's first "no-hit wonder."
Beyonce began the show, belting out her single "Irreplaceable" while vamping around the stage in a sparkly sequined minidress. The Pussycat Dolls also chose sequins for their performance, while Nelly Furtado opted for a skin-tight white dress and stick-straight hair.
Gwen Stefani made a stylish return to the music scene, performing the single "Wind It Up" from her forthcoming album, "The Sweet Escape." The new mom, wearing a skimpy sequined shift and a shoulder-length platinum bob, yodeled and rapped convincingly throughout the tune.
Not to be outdone, rapper Jay-Z stepped out of retirement and back into the spotlight, accompanied by scantily clad dancers as he performed the single "Show Me What You Got" from his new record, "Kingdom Come."
Lionel Richie made a festive return to the awards. Introduced by his diminutive daughter, Nicole Richie, the former Commodore performed a medley that included his '80s party anthem "All Night Long."
Barry Manilow performed a medley of favorites from his latest collection, "The Greatest Songs of the Sixties."
Some awards were announced off camera before the broadcast presentations.
The American Music Awards honor the best in pop/rock, country, soul/rhythm & blues, rap/hip hop, Latin, alternative, adult contemporary and contemporary inspirational music. Nominees were chosen based on record sales and winners were selected by a survey of about 20,000 listeners.